Initially, THC boosted brain metabolism and synaptic protein levels, indicative of heightened cognitive processes. Subsequently, it shifted towards reducing metabolic activities in the body akin to the effects seen with caloric restriction or intensive exercise, known for their anti-aging benefits.
Thanks this is a lot of great detail on the dosing mechanism that I think is really interesting. I love reading up on the experimental details and the actually components used to make these experiments work.
300mg of orally ingested THC spread out over 24 hours is about equivalent to consuming 1 typical candy/gummy every hour for 24 hours of the day. A reasonable or average or normal person would be uncomfortably high at these dosages. I also imagine the bioavailability of oral ingestion is less than the dosing mechanism you described although I’m not sure (is that getting taken up through the lymphatic system? How does it differ from oral ingestion or injection into the bloodstream?).
Fascinating stuff, thanks for sharing your knowledge.